Minoxidil 2% vs 5%: Which Strength Works Best for Hair Loss?

When it comes to treating hair loss, minoxidil, a topical medication approved by the FDA for androgenetic alopecia. Also known as Rogaine, it's one of the few over-the-counter treatments with proven results for men and women. The two most common strengths are minoxidil 2%, a milder formula often recommended for women and sensitive scalps, and minoxidil 5%, the stronger version typically used by men seeking faster or more visible regrowth. But which one actually works better—and is the higher dose worth the extra side effects?

Studies show that minoxidil 5%, applied once daily, leads to significantly more hair regrowth than the 2% version. In clinical trials, men using 5% saw up to 45% more hair density after 48 weeks compared to those on 2%. That doesn’t mean 2% doesn’t work—it does—but it works slower and often less noticeably. For women, 2% is still the standard recommendation, partly because higher concentrations can cause unwanted facial hair growth in some cases. But if you’re a man with early thinning or a receding hairline, 5% gives you a real shot at thicker, fuller hair. The key is consistency: you need to use it every day for at least 4 months before you see anything, and if you stop, you lose what you gained.

Side effects are usually mild but real. Both strengths can cause scalp dryness, itching, or flaking. The 5% version has a slightly higher chance of causing unwanted hair on the face or neck, especially if you’re not careful about application. It also comes in a higher alcohol content formula, which can sting if your scalp is irritated. If you’ve had bad reactions before, start with 2% and work your way up. Some people switch from 2% to 5% after a few months once their scalp adjusts. There’s no magic formula—just patience and persistence. What you’ll find below are real user experiences, direct comparisons, and practical advice from people who’ve tried both strengths. Whether you’re just starting out or wondering if you should upgrade, the posts here cut through the noise and give you what actually works.